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Product Name
Anti-Galectin 3 (7G9) Mouse antibody
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Description
Galectin 3 (7G9) Mouse monoclonal antibody
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Tested applications
WB, IHC-P, ELISA
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Species reactivity
Human, Mouse
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Isotype
IgG1
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Preparation
Antigen: Purified recombinant protein expressed in E.coli.
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Clonality
Monoclonal
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Formulation
PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/1;000-2;000 IHC1/100-200 ELISA 10;000-50;000
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Validations
Immunohistochemical analysis of paraffin-embedded human-colon2 using antibody diluted at 1:50.
Western blot detection of Galectin-3/LGALS3 in CHO-K1,Hela cell lysates using Galectin-3/LGALS3 (7G9) Mouse mAb(1:1000 diluted).Predicted band size:26KDa.Observed band size:26KDa.
Immunohistochemical analysis of paraffin-embedded human-colon using antibody diluted at 1:50.
Western blot analysis of 1)MCF7, 2) 3T3 with Galectin-3 Mouse mAb diluted at 1:2,000.
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Background
Swiss-Prot Acc.P17931.Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis . In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
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