Anti-FSTL1 antibody

Cat.#: 142750

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Product Information

  • Product Name
    Anti-FSTL1 antibody
  • Documents
  • Description
    Rabbit Polyclonal to Mouse FSTL1
  • Tested applications
    WB, ELISA
  • Species reactivity
    Mouse FSTL1
  • Alternative names
    Fstl antibody; TSC-36 antibody; AI316791 antibody; AW107808 antibody; FRP antibody; FSL1 antibody; MIR198 antibody; AI316791 antibody; AW107808 antibody; FLJ50214 antibody; FLJ52277 antibody; FRP antibody; FSL1 antibody; Fstl antibody; FSTL1 antibody; Fstl1 antibody; TSC-36 antibody
  • Immunogen
  • Isotype
    Rabbit IgG
  • Preparation
    Produced in rabbits immunized with purified, recombinant Mouse FSTL1 . FSTL1 specific IgG was purified by Mouse FSTL1 affinity chromatography.
  • Clonality
    Polyclonal
  • Formulation
    0.2 μm filtered solution in PBS
  • Storage instructions
    This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
    Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
  • Applications

    WB: 5-20 μg/ml

    ELISA: 0.1-0.2 μg/ml

    This antibody can be used at 0.1-0.2 μg/ml with the appropriate secondary reagents to detect Mouse FSTL1.

  • Validations

    FSTL1 Antibody, Rabbit PAb, Antigen Affinity Purified, Western blot

    FSTL1 Antibody, Rabbit PAb, Antigen Affinity Purified, Western blot

  • Background
    Follistatin-related protein 1 (FSTL1)  is an extracellular glycoprotein whose functional significance in physiological and pathological processes is incompletely understood. Recently, we have shown that FSTL1 acts as a muscle-derived secreted factor that is up-regulated by Akt activation and ischemic stress and that FSTL1 exerts favorable actions on the heart and vasculature. Here, we sought to identify the receptor that mediates the cellular actions of FSTL1. It contains an FS module, a follistatin-like sequence containing 10 conserved cysteine residues. FSTL1 is thought to be an autoantigen associated with rheumatoid arthritis. DIP2A functions as a novel receptor that mediates the cardiovascular protective effects of FSTL1. Experiment results have provided in vivo and in vitro evidence to demonstrate that Fstl1 modulates lung development and alveolar maturation, in part, through BMP4 signaling.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"