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Product Name
Anti-FGFR2 antibody
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Description
Rabbit polyclonal antibody to FGFR2
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Tested applications
WB, FC
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Species reactivity
Human
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Alternative names
BEK antibody; JWS antibody; BBDS antibody; CEK3 antibody; CFD1 antibody; ECT1 antibody; KGFR antibody; TK14 antibody; TK25 antibody; BFR-1 antibody; CD332 antibody; K-SAM antibody
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Isotype
IgG
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Preparation
This antigen of this antibody was recombinant protein within human fgfr2/cd332 aa 600-750 / 821.
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Clonality
Polyclonal
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Formulation
Liquid, 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage instructions
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
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Applications
WB: 1:1,000
IHC-P: 1:200
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Validations
Fig1: Western blot analysis on MCF-7 cell lysates using anti- CD332 rabbit polyclonal antibodies.
Fig2: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti- CD332 rabbit polyclonal antibody.
- Background
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References
- Fibroblast growth factor signalling: from development to cancer. Turner N., Grose R. Nat. Rev. Cancer 10:116-129(2010)
- FGFR2 abnormalities underlie a spectrum of bone, skin, and cancer pathologies. Katoh M. J. Invest. Dermatol. 129:1861-1867(2009)
- Cbl-mediated degradation of Lyn and Fyn induced by constitutive fibroblast growth factor receptor-2 activation supports osteoblast differentiation. Kaabeche K., Lemonnier J., Le Mee S., Caverzasio J., Marie P.J. J. Biol. Chem. 279:36259-36267(2004)
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"