Anti-ENO1 Rabbit antibody

Cat.#: 166952

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Product Information

  • Product Name
    Anti-ENO1 Rabbit antibody
  • Documents
  • Description
    ENO1 Rabbit polyclonal antibody
  • Tested applications
    WB, ICC/IF, FC, IP
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    2 phospho D glycerate hydro lyase; 2-phospho-D-glycerate hydro-lyase; Alpha enolase; Alpha enolase like 1; Alpha-enolase; C myc promoter binding protein; C-myc promoter-binding protein; EC 4.2.1.11; eno1; ENO1L1; ENOA_HUMAN; Enolase 1 (alpha); Enolase 1 ( antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human ENO1
  • Clonality
    Polyclonal
  • Formulation
    Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
  • Storage instructions
    Store at -20°C. Stable for 12 months from date of receipt.
  • Applications

    WB: 1/2000

    ICC/IF: 1/50

    FC: 1/20

    IP: 1/20

  • Validations

    Immunocytochemistry of ENO1(green) in Hela cells using ENO1 Rabbit pAb at dilution 1/50, and DAPI(blue)

    Immunocytochemistry of ENO1(green) in Hela cells using ENO1 Rabbit pAb at dilution 1/50, and DAPI(blue)

    Western blot detection of ENO1 in Jurkat,THP-1,C6 cell lysates using ENO1 Rabbit pAb(1:1000 diluted).Predicted band size:47KDa.Observed band size:47KDa.

    Western blot detection of ENO1 in Jurkat,THP-1,C6 cell lysates using ENO1 Rabbit pAb(1:1000 diluted).Predicted band size:47KDa.Observed band size:47KDa.

    Western blot detection of ENO1 in Jurkat cell lysates using ENO1 Rabbit pAb(1:1000 diluted).Predicted band size:47KDa.Observed band size:47KDa.

    Western blot detection of ENO1 in Jurkat cell lysates using ENO1 Rabbit pAb(1:1000 diluted).Predicted band size:47KDa.Observed band size:47KDa.

  • Background
    Swiss-Prot Acc.P06733.Multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production.MBP1 binds to the myc promoter and acts as a transcriptional repressor. May be a tumor suppressor.MiscellaneousUsed as a diagnostic marker for many tumors and, in the heterodimeric form, alpha/gamma, as a marker for hypoxic brain injury after cardiac arrest. Also marker for endometriosis. Antibodies against alpha-enolase are present in sera from patients with cancer-associated retinopathy syndrome (CAR), a progressive blinding disease which occurs in the presence of systemic tumor growth, primarily small-cell carcinoma of the lung and other malignancies. Is identified as an autoantigen in Hashimoto encephalopathy (HE) a rare autoimmune disease associated with Hashimoto thyroiditis (HT). HT is a disorder in which destructive processes overcome the potential capacity of thyroid replacement leading to hypothyroidism.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"