Anti-eIF4E Rabbit antibody

Cat.#: 167277

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Special Price 441.3 USD

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Product Information

  • Product Name
    Anti-eIF4E Rabbit antibody
  • Documents
  • Description
    eIF4E Rabbit polyclonal antibody
  • Tested applications
    WB, IHC-P, FC, IP
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    CBP; EIF4F; AUTS19; EIF4E1; eIF-4E; EIF4EL1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human eIF4E
  • Clonality
    Polyclonal
  • Formulation
    Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
  • Storage instructions
    Store at -20°C. Stable for 12 months from date of receipt.
  • Applications

    WB: 1/5000

    IHC: 1/20

    FC: 1/20

    IP: 1/20

  • Validations

    Western blot detection of eIF4E in K562,Rat Brain,C6,3T3,Hela cell lysates using eIF4E Rabbit pAb(1:1000 diluted).Predicted band size:25kDa.Observed band size:25kDa.

    Western blot detection of eIF4E in K562,Rat Brain,C6,3T3,Hela cell lysates using eIF4E Rabbit pAb(1:1000 diluted).Predicted band size:25kDa.Observed band size:25kDa.

    Immunohistochemistry of eIF4E in paraffin-embedded Human lung cancer tissue using eIF4E Rabbit pAb at dilution 1/20

    Immunohistochemistry of eIF4E in paraffin-embedded Human lung cancer tissue using eIF4E Rabbit pAb at dilution 1/20

  • Background
    Swiss-Prot Acc.P06730.Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"