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Product Name
Anti-ECSIT antibody
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Description
Rabbit polyclonal to ECSIT
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Tested applications
ELISA, WB, IHC-P
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Species reactivity
Human ECSIT
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Alternative names
SITPEC antibody; Sitpec antibody; ECSIT signalling integrator antibody; ECSIT antibody; SITPEC antibody; ECSIT homolog antibody; evolutionarily conserved signaling intermediate in Toll pathway antibody; mitochondrial antibody; likely ortholog of mouse signaling intermediate in Toll pathway evolutionarily conserved antibody; ECSIT homolog (Drosophila) antibody; Ecsit antibody; Sitpec antibody; evolutionarily conserved signaling intermediate in Toll pathway antibody; mitochondrial antibody; signaling intermediate in Toll pathway-evolutionarily conserved antibody
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Isotype
Rabbit IgG
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Preparation
Produced in rabbits immunized with purified, recombinant Human ECSIT (rh ECSIT; Q9BQ95-1; Glu246-Ser431). ECSIT specific IgG was purified by Human ECSIT affinity chromatography.
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Clonality
Polyclonal
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Formulation
0.2 μm filtered solution in PBS
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Storage instructions
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. -
Applications
WB: 10-20 μg/ml
ELISA: 0.1-0.2 μg/mL
This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human ECSIT. The detection limit for Human ECSIT is < 0.039 ng/well.
IHC-P: 0.1-1 μg/mL
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Background
Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity)..; FUNCTION: Required for efficient assembly of mitochondrial NADH:ubiquinone oxidoreductase.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"