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Product Name
Anti-DR5 (6F6) Mouse antibody
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Description
DR5 (6F6) Mouse monoclonal antibody
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Tested applications
WB
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Species reactivity
Human
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Alternative names
Fas like protein ;Apoptosis inducing protein TRICK2A/2B ;Apoptosis inducing receptor TRAIL R2 ;CD 262 ;CD262 ;CD262 antigen ;Cytotoxic TRAIL receptor 2 ;Death domain containing receptor for TRAIL/Apo 2L ;Death domain containing receptor for TRAIL/Apo2L ;D antibody
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Isotype
IgG2b
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Preparation
Antigen: Purified recombinant human DR5 protein fragments expressed in E.coli.
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Clonality
Monoclonal
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Formulation
Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/1000;Other 1/2000
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Validations
Western blot detection of DR5 in SW480,K562,HCT116 and Hela cell lysates using DR5 mouse mAb (1:1000 diluted).Predicted band size:40/48KDa.Observed band size:40/48KDa.
Western blot detection of DR5 in MCF-7 and T47D cell lysates using DR5 mouse mAb (1:2000 diluted).Predicted band size:40/48KDa.Observed band size:40/48KDa.
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Background
Swiss-Prot Acc.O14763.Plays an important role in the regulation of apoptosis in various physiological systems. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"