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Product Name
Anti-DNAJC30 antibody
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Description
Rabbit polyclonal to DNAJC30
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Tested applications
ELISA, IHC-P
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Species reactivity
Human DNAJC30
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Alternative names
DnaJ (Hsp40) homolog antibody; subfamily C antibody; member 30 antibody; DNAJC30 antibody; WBSCR18 antibody; Williams Beuren syndrome chromosome region 18 antibody; dnaJ homolog subfamily C member 30 antibody; williams-Beuren syndrome chromosomal region 18 protein antibody; DnaJ (Hsp40) homolog antibody; subfamily C antibody; member 30 antibody; Dnajc30 antibody; 1300007M11Rik antibody; Wbscr18 antibody; Williams-Beuren syndrome chromosome region 18 homolog antibody; Williams-Beuren syndrome critical region 18 antibody; dnaJ homolog subfamily C member 30 antibody; williams-Beuren syndrome chromosomal region 18 protein homolog antibody; Wbscr18 antibody; 1300007M11Rik antibody; WBSCR18 antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
Produced in rabbits immunized with purified, recombinant Human DNAJC30 (rh DNAJC30; Q96LL9; Ser39-Gly124). DNAJC30 specific IgG was purified by Human DNAJC30 affinity chromatography.
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Clonality
Polyclonal
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Formulation
0.2 μm filtered solution in PBS
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Storage instructions
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. -
Applications
ELISA: 0.1-0.2 μg/mL
This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human DNAJC30. The detection limit for Human DNAJC30 is < 0.039 ng/well.
IHC-P: 0.1-2 μg/mL
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Validations
DNAJC30 Antibody, Rabbit PAb, Antigen Affinity Purified
Immunochemical staining of human DNAJC30 in human kidney with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections).
DNAJC30 Antibody, Rabbit PAb, Antigen Affinity Purified
Immunochemical staining of human DNAJC30 in human spleen with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections).
DNAJC30 Antibody, Rabbit PAb, Antigen Affinity Purified
Immunochemical staining of human DNAJC30 in human heart with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections).
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Background
NAJC30 is a member of the DNAJ molecular chaperone homology domain-containing protein family. DNAJC30 gene is deleted in williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. DNAJC30 is expressed in brain, heart, kidney, liver, lung, spleen, stomach and testis. It contains 1 J domain. DNAJC30 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region.
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References
- Hillier L W, et al. (2003) The DNA sequence of human chromosome 7. Nature. 424:157-164.
- Ota T, et al. (2004) Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat Genet. 36:40-5.
- Merla G, et al. (2002) Identification of additional transcripts in the Williams-Beuren syndrome critical region. Hum Genet. 110:429-38.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"