Anti-DMBT1/Muclin antibody

Anti-DMBT1/Muclin antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit polyclonal to DMBT1/Muclin

ELISA, IHC-P

Human DMBT1 / GP340

apactin antibody; CRP antibody; CRP-[a] antibody; CRP-[b] antibody; Crpd antibody; crp-ductin antibody; DBMT1 antibody; Dmbt1 antibody; DMBT1 antibody; ebnerin antibody; FLJ61058 antibody; glycoprotein 300 antibody; glycoprotein 340 antibody; gp300 antibody; GP340 antibody; gp-340 antibody; hensin antibody; hensin antibody; MGC164738 antibody; Muclin antibody; Muclin antibody; p80 antibody; RP11-481L19.1 antibody; salivary agglutinin antibody; vomeroglandin antibody; p80 antibody; Crp antibody; GP340 antibody; muclin antibody; Crpd antibody; DBMT1 antibody; gp300 antibody; CRP-[a] antibody; CRP-[b] antibody

Rabbit IgG

Produced in rabbits immunized with purified, recombinant Human DMBT1 (rh DMBT1; NP_004397.2; Met 1-Ser 220). DMBT1 specific IgG was purified by human DMBT1 affinity chromatography

Polyclonal

0.2 μm filtered solution in PBS with 5% trehalose

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Deleted in malignant brain tumors 1 protein, also known as glycoprotein 340, surfactant pulmonary-associated D-binding protein, DMBT1 and GP340, is a secreted protein which belongs to the DMBT1 family. DMBT1 contains 2 CUB domains, 14 SRCR domains and 1 ZP domain. It is highly expressed in alveolar and macrophage tissues. In some macrophages, expression is detected on the membrane, and in other macrophages, it is strongly expressed in the phagosome/phagolysosome compartments. Defects in DMBT1 are involved in the development of glioma (GLM). Gliomas are central nervous system neoplasms derived from glial cells and comprise astrocytomas, glioblastoma multiforme, oligodendrogliomas , and ependymomas. DMBT1 may be considered as a candidate tumor suppressor for brain, lung, esophageal, gastric, and colorectal cancers. It may play roles in mucosal defense system, cellular immune defense and epithelial differentiation. DMBT1 may play a role as an opsonin receptor for SFTPD and SPAR in macrophage tissues throughout the body, including epithelial cells lining the gastrointestinal tract. It may be an important factor in fate decision and differentiation of transit-amplifying ductular (oval) cells within the hepatic lineage. DMBT1 may function as a binding protein in saliva for the regulation of taste sensation. It binds to HIV-1 envelope protein and has been shown to both inhibit and facilitate viral transmission.