Anti-CSRP1 antibody

Anti-CSRP1 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit polyclonal to CSRP1

ELISA, WB, IP

Mouse CSRP1

CRP antibody; CRP1 antibody; CRP1 antibody; CRP antibody; AA408841 antibody; AA959891 antibody; AW545626 antibody; CRP1 antibody; CRP1 antibody; Csrp antibody; CSRP antibody; Csrp1 antibody; CSRP1 antibody; CYRP antibody; D1S181E antibody; DKFZp686M148 antibody; CRP antibody; CSRP antibody; CYRP antibody; D1S181E antibody; HEL-141 antibody; Csrp antibody; AA408841 antibody; AA959891 antibody; AW545626 antibody

Rabbit IgG

Produced in rabbits immunized with purified, recombinant Mouse CSRP1 (rh CSRP1; P97315; Met1-Glu193). CSRP1 specific IgG was purified by Mouse CSRP1 affinity chromatography.

Polyclonal

0.2 μm filtered solution in PBS

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Mouse Cysteine and glycine-rich protein 1, also known as Cysteine-rich protein 1, CSRP1 and CSRP, is a member of the CSRP family which may be involved in regulatory processes important for development and cellular differentiation. CSRP1 contains two LIM zinc-binding domains. The LIM / double zinc-finger motif found in CSRP1 is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Zebrafish CSRP1 is expressed in the mesendoderm and its derivatives. CSRP1 interacts with Dishevelled 2 (Dvl2) and Diversin (Div), which control cell morphology and other dynamic cell behaviors via the noncanonical Wnt and JNK pathways. When CSRP1 message is knocked down, abnormal convergent extension cell movement is induced, resulting in severe deformities in midline structures. In addition, cardiac bifida is induced as a consequence of defects in cardiac mesoderm cell migration. CSRP1 acts as a key molecule of the noncanonical Wnt pathway, which orchestrates cell behaviors during dynamic morphogenetic movements of tissues and organs.

• Wimmer,U. et al., 2005, Nucleic acids Res. 33 (18):5715-27.
• Miyasaka, KY.et al., 2007, Proc Natl Acad Sci USA. 104 (27): 11274-9.
• Zhou,C.Z. et al., 2008,Chin Med J. 121 (24): 2479-86.
• Lilly,B. et al., 2010, Arterioscler Thromb Vasc Biol. 30 (4):694-701.