Anti-Coagulation Factor IX / FIX / F9 antibody

Cat.#: 103928

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Product Information

  • Product Name
    Anti-Coagulation Factor IX / FIX / F9 antibody
  • Documents
  • Description
    Rabbit monoclonal to Coagulation Factor IX / FIX / F9
  • Tested applications
    ELISA, WB
  • Species reactivity
    Human Coagulation Factor IX / FIX / F9
  • Alternative names
    FIX antibody; PTC antibody; HEMB antibody; THPH8 antibody; Cf9 antibody; Cf-9 antibody; AW111646 antibody; Cf9 antibody; Cf-9 antibody; Coagulation Factor IX antibody; Coagulation Factor IX antibody; F9 antibody; F9 antibody; FIX antibody; FIX antibody; HEMB antibody; MGC129642 antibody; P19 antibody; PTC antibody; RP23-419J18.1 antibody; RP6-88D7.1 antibody; AW111646 antibody; MGC129641 antibody; p19 antibody
  • Immunogen
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained from a rabbit immunized with purified, recombinant Human Coagulation Factor IX / FIX / F9 (rh Coagulation Factor IX / FIX / F9; AAB59620.1; Met 1-Thr 461).
  • Clonality
    Monoclonal
  • Formulation
    0.2 μm filtered solution in PBS with 5% trehalose
  • Storage instructions
    This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
    Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
  • Applications

    WB: 10-20 μg/ml

    ELISA: 0.1-0.2 μg/mL

    This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human F9. The detection limit for Human F9 is approximately 0.00245 ng/well.

  • Validations

    Coagulation Factor IX / FIX / F9 Antibody, Rabbit MAb, Western blot

    Coagulation Factor IX / FIX / F9 Antibody, Rabbit MAb, Western blot

  • Background
    Coagulation factor IX, also known as Christmas factor, Plasma thromboplastin component and PTC, is a secreted protein which belongs to the peptidase S1 family. Coagulation factor IX / F9 contains two EGF-like domains, one Gla (gamma-carboxy-glutamate) domain and one?peptidase S1 domain. Coagulation factor IX / F9 is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca2+ons, phospholipids, and factor VIIIa. Defects in Coagulation factor IX / F9 are the cause of thrombophilia due to factor IX defect which is a hemostatic disorder characterized by a tendency to thrombosis. Defects in Coagulation factor IX / F9 are also the cause of recessive X-linked hemophilia B ( HEMB ) which also known as Christmas disease.
  • References
    • Onay U.V., et al., 2003, Br. J. Haematol. 120:656-659.
    • Vidal F., et al., 2000, Br. J. Haematol. 111:549-551.
    • Simioni P., et al., 2009, N. Engl. J. Med. 361:1671-1675.
    • Espinos C., et al., 2009, Haematologica 88:235-236.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"