Anti-CD40 antibody

Anti-CD40 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Mouse Monoclonal to Rat CD40

FCM

Rat CD40/TNFRSF5

p50 antibody; gp39 antibody; HIGM1 antibody; IGM antibody; IMD3 antibody; T-BAM antibody; TRAP antibody; p50 antibody; Bp50 antibody; CDW40 antibody; TNFRSF5 antibody; IGM antibody; p50 antibody; Bp50 antibody; GP39 antibody; IMD3 antibody; TRAP antibody; HIGM1 antibody; T-BAM antibody; Tnfrsf5 antibody; AI326936 antibody; AI326936 antibody; Bp50 antibody; Bp50 antibody; CD40 antibody; Cd40 antibody; CDW40 antibody; MGC9013 antibody; p50 antibody; RP23-428M13.1 antibody; TNFRSF5 antibody; Tnfrsf5 antibody

Mouse IgG1

This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rat CD40/TNFRSF5 and conjugated with APC under optimum conditions, the unreacted APC was removed.

Monoclonal

Aqueous solution containing 0.5% BSA and 0.09% sodium azide

This antibody is stable for 12 months from date of receipt when stored at 2℃-8℃. Protected from prolonged exposure to light. Do not freeze !
Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

FCM

CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 protein is expressed in B cells, dendritic cells, macrophages, endothelial cells, and several tumor cell lines. Defects in CD40 result in hyper-IgM immunodeficiency type 3 (HIGM3). In addition, CD40/CD40L interaction is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis.

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