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Product Name
Anti-CD200R1 antibody
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Description
Mouse monoclonal to CD200R1
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Tested applications
FCM
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Species reactivity
Human CD200R1
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Alternative names
CD200R antibody; CD200R antibody; CD200R1 antibody; Cd200r1 antibody; HCRTR2 antibody; MOX2R antibody; Mox2r antibody; OX2R antibody; OX2R antibody; OX2R antibody; Mox2r antibody; CD200R antibody; OX2R antibody; MOX2R antibody; CD200R antibody; HCRTR2 antibody
- Immunogen
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Isotype
Mouse IgG1
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Preparation
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD200R1 (rh CD200R1; AAI43394.1; Met1-Leu266) and conjugated with PE under optimum conditions, the unreacted PE was removed.
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Clonality
Monoclonal
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Formulation
Aqueous solution containing 0.5% BSA and 0.09% sodium azide
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Storage instructions
This antibody is stable for 12 months from date of receipt when stored at 2℃-8℃. Protected from prolonged exposure to light. Do not freeze !
Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. -
Applications
FCM
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Validations
CD200R1 Antibody (PE), Mouse MAb, Flow Cytometry
Flow cytometric analysis of Human CD200R1 expression on human whole blood lymphocytes. Cells were stained with PE-conjugated anti-Human CD200R1. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes.
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Background
The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cell surface glycoprotein CD200 receptor 1 (CD200R1) is an isoform of CD200 receptors which is expressed on cells of the myeloid lineage. CD200R1 is a receptor for the OX-2 membrane glycoprotein. The receptor-substrate interaction may serve as a myeloid downregulatory signal.
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References
- Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
- Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
- Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"