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Product Name
Anti-CD147 Rabbit antibody
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Description
CD147 Rabbit monoclonal antibody
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Tested applications
WB, ICC/IF, FC, IP
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Species reactivity
Mouse
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Alternative names
HT-7; CD147; EMMPRIN; AI115436; AI325119 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant protein of mouse CD147
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Clonality
Monoclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/2000
ICC/IF: 1/50
FC: 1/50
IP: 1/20
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Validations
Western blot detection of CD147 in Rat Brain,C6,3T3 cell lysates using CD147 Rabbit mAb(1:1000 diluted).Predicted band size:43kDa.Observed band size: 38-58kDa.
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Background
Swiss-Prot Acc.P18572.Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3, SLC16A8, SLC16A11 and SLC16A12 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"