Anti-Bad Rabbit antibody

Cat.#: 166803

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Product Information

  • Product Name
    Anti-Bad Rabbit antibody
  • Documents
  • Description
    Bad Rabbit polyclonal antibody
  • Tested applications
    WB, IHC-P, ICC/IF, FC, IP
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    BBC2; BCL2L8 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human Bad
  • Clonality
    Polyclonal
  • Formulation
    Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
  • Storage instructions
    Store at -20°C. Stable for 12 months from date of receipt.
  • Applications

    WB: 1/1000

    IHC: 1/50

    ICC/IF: 1/50

    FC: 1/20

    IP: 1/20

  • Validations

    Western blot detection of Bad in Rat Brain,C6,3T3,Hela cell lysates using Bad Rabbit pAb(1:1000 diluted).Predicted band size:18kDa.Observed band size:23kDa.

    Western blot detection of Bad in Rat Brain,C6,3T3,Hela cell lysates using Bad Rabbit pAb(1:1000 diluted).Predicted band size:18kDa.Observed band size:23kDa.

    Immunohistochemistry of Bad in paraffin-embedded Human breast cancer tissue using Bad Rabbit pAb at dilution 1/50

    Immunohistochemistry of Bad in paraffin-embedded Human breast cancer tissue using Bad Rabbit pAb at dilution 1/50

    Immunocytochemistry of Bad(green) in Hela cells using Bad Rabbit pAb at dilution 1/50, and DAPI(blue)

    Immunocytochemistry of Bad(green) in Hela cells using Bad Rabbit pAb at dilution 1/50, and DAPI(blue)

  • Background
    Swiss-Prot Acc.Q92934.Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 . Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"