alpha 1 Antichymotrypsin / AACT antibody

alpha 1 Antichymotrypsin / AACT antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

alpha 1 Antichymotrypsin / AACT Rabbit Polyclonal antibody. Positive WB detected in human blood tissue, COLO 320 cells, human colon tissue. Positive IHC detected in human liver tissue, human spleen tissue. Observed molecular weight by Western-blot: 44-70 kDa

ELISA, IHC, WB

Human; other species not tested.

A1 Antichymotrypsin antibody; AACT antibody; ACT antibody; Alpha 1 antichymotrypsin antibody; GIG24 antibody; GIG25 antibody; Serpin A3 antibody; SERPINA3 antibody

Rabbit IgG

This antibody was obtained by immunization of alpha 1 Antichymotrypsin / AACT recombinant protein (Accession Number: NM_001384672). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Human SerpinA3, also known as Alpha 1-antichymotrypsin (AACT), is a member of the serine protease inhibitor class, and is a plasma alpha globulin glycoprotein which increases in the blood during the inflammatory process. SerpinA3, is also an inhibitor of neutrophil cathepsin G, mast cell chymases and pancreatic chymotrypsin. SerpinA3 is produced primarily in the liver, and is identified as an acute-phase inflammatory protein. SerpinA3 deficiency has been associated with liver disease. SerpinA3 has also been implicated in the pathology of a number of devastating human diseases including chronic obstructive pulmonary disease (COPD), Parkinson’s disease (PD), Alzheimer’s disease (AD), Stroke, Cystic Fibrosis, Cerebral Haemorrhage and Multiple System Atrophy.