-
Product Name
Human Adiponectin/Acrp30 (Fc Tag) recombinant protein
- Documents
-
Description
Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
-
Protein name
Adiponectin
-
Protein short names
APM1; APM-1; 30KDA; APN; ACRP30; ADIPONECTIN; ADIPO; ADIPQTL1; GBP28; AD; ADIPOQ; ACDC; ADPN
-
Uniprot ID
Q15848
-
Gene Name
ADIPOQ; ACDC; ACRP30; APM1; GBP28
-
Source/Expression Host
Human Cells
-
Expression Plasmid/cDNA
A DNA sequence encoding the human ADIPOQ (Q15848) (Met1-Asn244) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
-
Protein Species
Human
-
Molecular weight
The recombinant human ADIPOQ comprises 467 amino acids and has a predicted molecular mass of 51.6 kDa.
-
Purity
> 80 % as determined by SDS-PAGE
-
Validations
Human Adiponectin / Acrp30 / ADIPOQ Protein (Fc Tag) SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"