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Product Name
ABCC6 Polyclonal Antibody
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Description
Polyclonal antibody to ABCC6
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Tested applications
WB
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Species reactivity
Mouse, Rat
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Alternative names
ABCC6 antibody; ABC34 antibody; ARA antibody; EST349056 antibody; GACI2 antibody; MLP1 antibody; MOAT-E antibody; MOATE antibody; MRP6 antibody; PXE antibody; PXE1 antibody; URG7 antibody; multidrug resistance-associated protein 6 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 830-940 of human ABCC6 (NP_001162.4).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
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Validations
Western blot - ABCC6 Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using ABCC6 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 30s.
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Background
Isoform 1: May participate directly in the active transport of drugs into subcellular organelles or influence drug distribution indirectly. Transports glutathione conjugates as leukotriene-c4 (LTC4) and N-ethylmaleimide S-glutathione (NEM-GS).; Isoform 2: Inhibits TNF-alpha-mediated apoptosis through blocking one or more caspases.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"