pSPV-EGFP vector (V003058) Gene synthesis in pSPV-EGFP backbone

Price Information

Cat No. Plasmid Name Availability Buy one, get one free! (?)
V003058 pSPV-EGFP In stock, instant shipping

Two tubes of lyophilized plasmid will be delivered, each tube is about 5µg.

Basic Vector Information

Vector Name:
pSPV-EGFP
Antibiotic Resistance:
Ampicillin
Length:
3457 bp
Type:
Poxvirus recombinant transfer vector
Replication origin:
ori
Source/Author:
Luo S, Peng Y, Diel DG, Rock DL.
Growth Strain(s):
DH10B
Growth Temperature:
37℃

pSPV-EGFP vector Map

pSPV-EGFP3457 bp6001200180024003000multiple cloning site 1 (MCS)early-late Vaccinia virus (VACV) VV7.5 promoterEGFPmultiple cloning site 2 (MCS2)T7 promoteroriAmpRAmpR promoterSP6 promoter

Plasmid Protocol

1. Centrifuge at 5,000×g for 5 min.

2. Carefully open the tube and add 20 μl of sterile water to dissolve the DNA.

3. Close the tube and incubate for 10 minutes at room temperature.

4. Briefly vortex the tube and then do a quick spin to concentrate the liquid at the bottom. Speed is less than 5000×g.

5. Store the plasmid at -20 ℃.

6. The concentration of plasmid re-measurement sometimes differs from the nominal value, which may be due to the position of the lyophilized plasmid in the tube, the efficiency of the re-dissolution, the measurement bias, and adsorption on the wall of the tube, therefore, it is recommended to transform and extract the plasmid before using it

General Plasmid Transform Protocol

1. Take one 100μl of the competent cells and thaw it on ice for 10min, add 2μl of plasmid, then ice bath for 30min, then heat-shock it at 42℃ for 60s, do not stir, and then ice bath for 2min.

2. Add 900μl of LB liquid medium without antibiotics, and incubate at 37℃ for 45min (30℃ for 1-1.5 hours) with 180rpm shaking.

3. Centrifuge at 6000rpm for 5min, leave only 100μl of supernatant to resuspend the bacterial precipitate and spread it onto the target plasmid-resistant LB plate.

4. Invert the plate and incubate at 37℃ for 14h, or at 30℃ for 20h.

5. Pick a single colony into LB liquid medium, add the corresponding antibiotics, incubate at 220rpm for 14h, and extract the plasmid according to the experimental needs and the instructions of the plasmid extraction kit.

pSPV-EGFP vector Sequence

LOCUS       40924_41190        3457 bp DNA     circular SYN 18-DEC-2018
DEFINITION  Poxvirus recombinant transfer vector pSPV-EGFP, complete sequence.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      synthetic DNA construct
  ORGANISM  synthetic DNA construct
REFERENCE   1  (bases 1 to 3457)
  AUTHORS   Luo S, Peng Y, Diel DG, Rock DL.
  TITLE     Virus recombinant transfer vector pSPV-EGFP
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 3457)
  AUTHORS   Luo S, Peng Y, Diel DG, Rock DL.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2009) Pathobiology, University of Illinois at 
            Urbana-Champaign, 2001 S. Lincoln Avenue, Urbana, IL 61802, USA
REFERENCE   3  (bases 1 to 3457)
  TITLE     Direct Submission
REFERENCE   4  (bases 1 to 3457)
  AUTHORS   .
  TITLE     Direct Submission
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: 
            "Unpublished"
COMMENT     SGRef: number: 2; type: "Journal Article"; journalName: "Submitted 
            (05-OCT-2009) Pathobiology, University of Illinois at 
            Urbana-Champaign, 2001 S. Lincoln Avenue, Urbana, IL 61802, USA"
COMMENT     SGRef: number: 3; type: "Journal Article"
FEATURES             Location/Qualifiers
     source          1..3457
                     /mol_type="other DNA"
                     /organism="synthetic DNA construct"
     misc_feature    4..33
                     /label=multiple cloning site 1 (MCS)
                     /note="multiple cloning site 1 (MCS)"
     regulatory      52..320
                     /label=early-late Vaccinia virus (VACV) VV7.5 promoter
                     /note="early-late Vaccinia virus (VACV) VV7.5 promoter"
                     /regulatory_class="promoter"
     CDS             340..1056
                     /label=EGFP
                     /note="enhanced GFP"
     misc_feature    1060..1085
                     /label=multiple cloning site 2 (MCS2)
                     /note="multiple cloning site 2 (MCS2)"
     promoter        complement(1095..1113)
                     /label=T7 promoter
                     /note="promoter for bacteriophage T7 RNA polymerase"
     rep_origin      complement(1371..1959)
                     /direction=LEFT
                     /label=ori
                     /note="high-copy-number ColE1/pMB1/pBR322/pUC origin of 
                     replication"
     CDS             complement(2133..2990)
                     /label=AmpR
                     /note="beta-lactamase"
     promoter        complement(2991..3095)
                     /label=AmpR promoter
     promoter        3441..3457
                     /label=SP6 promoter
                     /note="promoter for bacteriophage SP6 RNA polymerase"