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Product Name
Recombinant KCTD2 protein (His tag)
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Description
Recombinant Human KCTD2 BTB Domain Fragment (aa 72-263) – A high-purity protein fragment designed for studying the specific functions of the BTB domain in potassium channel tetramerization and protein-protein interactions, offering researchers a targeted tool for structural and functional analyses.
The full-length BTB/POZ domain-containing protein KCTD2, encoded by the gene KCTD2 in Homo sapiens, is involved in potassium channel assembly and regulation through its tetramerization domain. While specific functional summaries and subcellular localization details are not provided, KCTD2's BTB domain is critical for mediating protein-protein interactions and complex formation, highlighting its importance in cellular signaling and ion channel function. This recombinant fragment focuses on the BTB domain to enable precise investigation of its mechanistic roles.
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Protein name
BTB/POZ domain-containing protein KCTD2
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Uniprot ID
Q14681
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Gene Name
KCTD2; KIAA0176
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Source/Expression Host
E. coli
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Expression Plasmid
DNA encoding 72-263 aa (Q14681) were fused with C-terminal 6His tag.
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Sequence
MSKIKRWVRL NVGGTYFVTT RQTLGREPKS FLCRLCCQED PELDSDKDET GAYLIDRDPT YFGPILNYLR HGKLIITKEL AEEGVLEEAE FYNIASLVRL VKERIRDNEN RTSQGPVKHV YRVLQCQEEE LTQMVSTMSD GWKFEQLISI GSSYNYGNED QAEFLCVVSR ELNNSTNGIV IEPSEKAKIL QERGSRMLEH HHHHH
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 23.75 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 26 kDa band.
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Purity
>85%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Validations
Recombinant KCTD2 protein (His tag) SDS-PAGE
M: Marker; Lane 1: KCTD2; Lane 2: BSA
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"