pAAV-attR1-Chl-ccdb-attR2 vector (V018033)

Basic Vector Information

Vector Name:
pAAV-attR1-Chl-ccdb-attR2
Antibiotic Resistance:
Ampicillin
Length:
5016 bp
Type:
Protein expression
Replication origin:
ori
Host:
Mammalian cells, Adeno-associated virus
Promoter:
CMV
5' Primer:
Forward(left ITR)
Growth Strain(s):
DB3.1
Growth Temperature:
37℃

pAAV-attR1-Chl-ccdb-attR2 vector Map

pAAV-attR1-Chl-ccdb-attR25016 bp6001200180024003000360042004800AAV2 ITRpoly(A) signalpause siteattR1lac UV5 promoterCmRccdBattR2SV40 poly(A) signalAAV2 ITRf1 oriAmpR promoterAmpRori

pAAV-attR1-Chl-ccdb-attR2 vector Sequence

LOCUS       .                       5016 bp    DNA     circular UNK 01-JAN-1980
DEFINITION  synthetic circular DNA.
ACCESSION   
VERSION     
KEYWORDS    .
SOURCE      .
  ORGANISM  .
            .
FEATURES             Location/Qualifiers
     repeat_region   complement(1..141)
                     /label="AAV2 ITR"
                     /note="inverted terminal repeat of adeno-associated virus
                     serotype 2"
     polyA_signal    156..204
                     /label="poly(A) signal"
                     /note="synthetic polyadenylation signal"
     misc_feature    218..309
                     /label="pause site"
                     /note="RNA polymerase II transcriptional pause signal from
                     the human α2 globin gene"
     protein_bind    355..479
                     /label="attR1"
                     /note="recombination site for the Gateway® LR reaction"
     promoter        516..546
                     /label="lac UV5 promoter"
                     /note="E. coli lac promoter with an 'up' mutation"
     CDS             600..1256
                     /label="CmR"
                     /note="chloramphenicol acetyltransferase"
     CDS             1601..1903
                     /label="ccdB"
                     /note="CcdB, a bacterial toxin that poisons DNA gyrase"
     protein_bind    complement(1947..2071)
                     /label="attR2"
                     /note="recombination site for the Gateway® LR reaction"
     polyA_signal    complement(2129..2250)
                     /label="SV40 poly(A) signal"
                     /note="SV40 polyadenylation signal"
     repeat_region   2279..2419
                     /label="AAV2 ITR"
                     /note="inverted terminal repeat of adeno-associated virus
                     serotype 2"
     rep_origin      2494..2949
                     /label="f1 ori"
                     /note="f1 bacteriophage origin of replication; arrow
                     indicates direction of (+) strand synthesis"
     promoter        3231..3335
                     /label="AmpR promoter"
     CDS             3336..4193
                     /label="AmpR"
                     /note="β-lactamase"
     rep_origin      4367..4955
                     /label="ori"
                     /note="high-copy-number ColE1/pMB1/pBR322/pUC origin of
                     replication"

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