pT7-PE7 for IVT vector (V018001)

Basic Vector Information

Vector Name:
pT7-PE7 for IVT
Antibiotic Resistance:
Ampicillin
Length:
10552 bp
Type:
Gene-editing vector
Replication origin:
ori
Host:
E. coli
Promoter:
T7
5' Primer:
CMV-F
Growth Strain(s):
Stable
Growth Temperature:
37℃

pT7-PE7 for IVT vector Map

pT7-PE7 for IVT10552 bp5001000150020002500300035004000450050005500600065007000750080008500900095001000010500CMV promoterCas9(H840A)SV40 NLSSV40 NLSc-myc NLSbGH poly(A) signallac promoterCAP binding siteoriAmpRAmpR promoterCMV enhancer

pT7-PE7 for IVT vector Sequence

LOCUS       .                      10552 bp    DNA     circular UNK 01-JAN-1980
DEFINITION  synthetic circular DNA.
ACCESSION   
VERSION     
KEYWORDS    .
SOURCE      .
  ORGANISM  .
            .
FEATURES             Location/Qualifiers
     promoter        1..204
                     /label="CMV promoter"
                     /note="human cytomegalovirus (CMV) immediate early
                     promoter"
     CDS             340..360
                     /label="SV40 NLS"
                     /note="nuclear localization signal of SV40 (simian virus
                     40) large T antigen"
     CDS             358..4461
                     /label="Cas9(H840A)"
                     /note="nickase mutant of the Cas9 endonuclease from the
                     Streptococcus pyogenes Type II CRISPR/Cas system"
     CDS             4519..4539
                     /label="SV40 NLS"
                     /note="nuclear localization signal of SV40 (simian virus
                     40) large T antigen"
     CDS             7318..7338
                     /label="SV40 NLS"
                     /note="nuclear localization signal of SV40 (simian virus
                     40) large T antigen"
     CDS             7348..7374
                     /label="c-myc NLS"
                     /note="nuclear localization signal of human c-Myc
                     proto-oncogene (Dang and Lee, 1988)"
     polyA_signal    7482..7706
                     /label="bGH poly(A) signal"
                     /note="bovine growth hormone polyadenylation signal"
     promoter        complement(7825..7855)
                     /label="lac promoter"
                     /note="promoter for the E. coli lac operon"
     protein_bind    complement(7870..7891)
                     /label="CAP binding site"
                     /note="CAP binding activates transcription in the presence
                     of cAMP."
     rep_origin      complement(8179..8767)
                     /label="ori"
                     /note="high-copy-number ColE1/pMB1/pBR322/pUC origin of
                     replication"
     CDS             complement(8941..9798)
                     /label="AmpR"
                     /note="β-lactamase"
     promoter        complement(9799..9903)
                     /label="AmpR promoter"
     enhancer        10173..10552
                     /label="CMV enhancer"
                     /note="human cytomegalovirus immediate early enhancer"

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