pCAGGS-mCherry vector (V017850)

Basic Vector Information

Vector Name:
pCAGGS-mCherry
Antibiotic Resistance:
Ampicillin
Length:
5488 bp
Type:
Protein expression
Replication origin:
ori
Host:
Mammalian cells
Promoter:
CAG
5' Primer:
pcaggs-F
Growth Strain(s):
DH5a
Growth Temperature:
37℃

pCAGGS-mCherry vector Map

pCAGGS-mCherry5488 bp60012001800240030003600420048005400chimeric intronmCherryβ-globin poly(A) signalM13 revlac operatorlac promoterCAP binding siteSV40 promoterSV40 poly(A) signaloriAmpRAmpR promoter

pCAGGS-mCherry vector Sequence

LOCUS       .                       5488 bp    DNA     circular UNK 01-JAN-1980
DEFINITION  synthetic circular DNA.
ACCESSION   
VERSION     
KEYWORDS    .
SOURCE      .
  ORGANISM  .
            .
FEATURES             Location/Qualifiers
     intron          663..1680
                     /label="chimeric intron"
                     /note="chimera between introns from chicken β-actin and
                     rabbit β-globin"
     CDS             1762..2469
                     /label="mCherry"
                     /note="monomeric derivative of DsRed fluorescent protein
                     (Shaner et al., 2004)"
     polyA_signal    2576..2631
                     /label="β-globin poly(A) signal"
                     /note="rabbit β-globin polyadenylation signal (Gil and
                     Proudfoot, 1987)"
     primer_bind     complement(2992..3008)
                     /label="M13 rev"
                     /note="common sequencing primer, one of multiple similar
                     variants"
     protein_bind    complement(3016..3032)
                     /label="lac operator"
                     /note="The lac repressor binds to the lac operator to
                     inhibit transcription in E. coli. This inhibition can be
                     relieved by adding lactose or
                     isopropyl-β-D-thiogalactopyranoside (IPTG)."
     promoter        complement(3040..3070)
                     /label="lac promoter"
                     /note="promoter for the E. coli lac operon"
     protein_bind    complement(3084..3105)
                     /label="CAP binding site"
                     /note="CAP binding activates transcription in the presence
                     of cAMP."
     promoter        3163..3359
                     /label="SV40 promoter"
                     /note="SV40 early promoter"
     polyA_signal    3365..3499
                     /label="SV40 poly(A) signal"
                     /note="SV40 polyadenylation signal"
     rep_origin      complement(3737..4325)
                     /label="ori"
                     /note="high-copy-number ColE1/pMB1/pBR322/pUC origin of
                     replication"
     CDS             complement(4499..5356)
                     /label="AmpR"
                     /note="β-lactamase"
     promoter        complement(5357..5461)
                     /label="AmpR promoter"

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