Recombinant VSIG4 protein (His tag)

Recombinant VSIG4 protein (His tag)

Cat.#: 548545

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Product Information

  • Product Name
    Recombinant VSIG4 protein (His tag)
  • Documents
  • Description

    Recombinant Human VSIG4 Fragment (aa 20-234) - A high-quality research tool containing the complete Ig-like 1 and Ig-like 2 domains of Protein Z39Ig, designed for studying T-cell regulation and complement pathway inhibition.

    V-set and immunoglobulin domain-containing protein 4 (VSIG4/Protein Z39Ig) functions as a phagocytic receptor and serves as a strong negative regulator of T-cell proliferation and IL2 production. This membrane protein also acts as a potent inhibitor of the alternative complement pathway convertases, playing crucial roles in immune regulation. As a single-pass type I membrane protein, VSIG4 is localized to the cell membrane where it mediates these important immunomodulatory functions.

  • Protein name
    V-set and immunoglobulin domain-containing protein 4
  • Uniprot ID
    Q9Y279
  • Gene Name
    VSIG4; CRIg; Z39IG
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    DNA encoding 20-234 aa (Q9Y279) were fused with 6His tag.
  • Sequence
    20-234
  • Protein Species
    Human
  • Molecular weight
    Predictes a molecular mass of 25.53 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 26 kDa band.
  • Purity
    >86%, by SDS-PAGE with Coomassie Brilliant Blue staining.
  • Activity
    Not tested.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"