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Product Name
Recombinant VSIG4 protein (His tag)
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Description
Recombinant Human VSIG4 Fragment (aa 20-234) - A high-quality research tool containing the complete Ig-like 1 and Ig-like 2 domains of Protein Z39Ig, designed for studying T-cell regulation and complement pathway inhibition.
V-set and immunoglobulin domain-containing protein 4 (VSIG4/Protein Z39Ig) functions as a phagocytic receptor and serves as a strong negative regulator of T-cell proliferation and IL2 production. This membrane protein also acts as a potent inhibitor of the alternative complement pathway convertases, playing crucial roles in immune regulation. As a single-pass type I membrane protein, VSIG4 is localized to the cell membrane where it mediates these important immunomodulatory functions.
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Protein name
V-set and immunoglobulin domain-containing protein 4
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Uniprot ID
Q9Y279
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Gene Name
VSIG4; CRIg; Z39IG
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 20-234 aa (Q9Y279) were fused with 6His tag.
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Sequence
20-234
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 25.53 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 26 kDa band.
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Purity
>86%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"