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  • VPYPQ peptide

VPYPQ peptide

Not For Human Use, Lab Use Only.

Cat.#: 319351

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* Buy 1 get 1 free (?) What is TFA?

Special Price 94.20 USD

Availability: 1-2 weeks
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Product Information

  • Product Name
    VPYPQ peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    H-VPYPQ-OH
  • Sequence
    H-Val-Pro-Tyr-Pro-Gln-OH
  • Length (aa)
    5
  • Peptide Purity (HPLC)
    95.94%
  • Molecular Formula
    C29H42N6O8
  • Molecular Weight
    602.68
  • Source
    Synthetic
  • Form
    Powder
  • Description
    VPYPQ is a casein-derived peptide which was the most potent DPP-IV inhibitory peptide among them with an IC50 value of 41.45 μM. VPYPQ was resistant to hydrolysis by gastrointestinal enzymes and was relatively more stable to hydrolysis by DPP-IV and peptidases in plasma compared with its fragments. VPYPQ was a promising casein-derived DPP-IV inhibitor.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Zheng L, Xu Q, Lin L, Zeng XA, Sun B, Zhao M. In Vitro Metabolic Stability of a Casein-Derived Dipeptidyl Peptidase-IV (DPP-IV) Inhibitory Peptide VPYPQ and Its Controlled Release from Casein by Enzymatic Hydrolysis. J Agric Food Chem. 2019 Sep 25;67(38):10604-10613. doi: 10.1021/acs.jafc.9b03164. Epub 2019 Sep 12. PMID: 31466448.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"