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Product Name
Recombinant VGLL4 protein (His tag)
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Description
Recombinant Human Transcription Cofactor Vestigial-like Protein 4 (Vgl-4) Fragment (aa 206-290) is a highly stable and soluble protein unit designed for structural and biochemical studies. This 85-amino acid fragment retains key properties for investigating Vgl-4's role as a transcriptional coactivator.
The full-length Transcription Cofactor Vestigial-like Protein 4 (Vgl-4), encoded by the VGLL4 gene in Homo sapiens, functions as a specific coactivator for mammalian TEFs (Transcriptional Enhancer Factors), playing a crucial role in regulating gene expression. It is localized to the nucleus, where it participates in transcriptional mechanisms essential for cellular processes. The selected fragment (aa 206-290) was computationally optimized to provide a stable and soluble representation for experimental applications, enabling detailed analysis of Vgl-4's functional attributes.
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Protein name
Transcription cofactor vestigial-like protein 4
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Uniprot ID
Q14135
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Gene Name
VGLL4; KIAA0121
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 206-290 aa (Q14135) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 10.66 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 11 kDa band.
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Purity
>89%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"