VCT-VT2 peptide

VCT-VT2 peptide

• COA/MS/HPLC Report
• Handling and Storage of Synthetic Peptides
• Material Safety Data Sheets (MSDS)

Batch to batch variation of the purity

FLPIIGKLLSG

Phe-Leu-Pro-Ile-Ile-Gly-Lys-Leu-Leu-Ser-Gly

11

98.2%

Synthetic

Powder

This may be a degradation product of VCT-VT1. Active against Gram-positive S. aureus ATCC25923 (MIC 2.5 uM), E. faecalis ATCC29212 (MIC 20 uM), S. aureus (IS 10#) (MIC 10 uM), S. aureus (IS 37#) (MIC 5 uM), Gram-negative E. coli ATCC25922 (MIC 5 uM), E. cloacae ATCC13047 (MIC 2.5 uM), K. pneumonia ATCC700603 (MIC 10 uM), B. pyocyaneus CMCCB1010 (MIC 20 uM), P. aeruginosa ATCC27853 (MIC 40 uM), B. dysenteriae (MIC 5 uM), E. coli (IS 37#) (MIC 20 uM), E. coli (IS 117#) (MIC 5 uM), E. coli (IS 218#) (MIC 20 uM), P. aeruginosa (IS 350#) (MIC 10 uM), K. pneumonia (IS 59#) (MIC 80 uM), fungi C. albicans ATCC2002 (MIC 10 uM), C. albicans ATCC90028 (MIC 20 uM), and C. parapsilosis ATCC22019 (MIC 5 uM). VCT-VT2 was found in venom gland, the social wasp, Vespa tropica.

Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• Yang X, Wang Y, Lee WH, Zhang Y. Antimicrobial peptides from the venom gland of the social wasp Vespa tropica. Toxicon. 2013;74:151-7.

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.