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  • VCAM-1 binding peptide

VCAM-1 binding peptide

Not For Human Use, Lab Use Only.

Cat.#: 319169

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* Buy 1 get 1 free (?) What is TFA?

Special Price 110.40 USD

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Product Information

  • Product Name
    VCAM-1 binding peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    H-VHPKQHRGGSKGC-OH
  • Sequence
    H-Val-His-Pro-Lys-Gln-His-Arg-Gly-Gly-Ser-Lys-Gly-Cys-OH
  • Length (aa)
    13
  • Peptide Purity (HPLC)
    98.31%
  • Molecular Formula
    C57H95N23O16S
  • Molecular Weight
    1390.57
  • Source
    Synthetic
  • Form
    Powder
  • Description
    Vascular cell adhesion molecule-1 binding peptide (VCAM-1 binding peptide, sequence: VHPKQHRGGSKGC) showed high affinity for endothelial cells expressing VCAM-1 but low affinity for macrophages or smooth muscle cells. This peptide potentially allows early detection of atherosclerosis.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Kelly KA, Nahrendorf M, Yu AM, Reynolds F, Weissleder R. In vivo phage display selection yields atherosclerotic plaque targeted peptides for imaging. Mol Imaging Biol. 2006 Jul-Aug;8(4):201-7.
    • Leung K. VHPKQHRGGSKGC-liquid perfluorocarbon nanoparticles. 2010 Feb 28 [updated 2010 Apr 1]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 20641979.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"