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Product Name
Recombinant UTER protein (His tag)
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Description
Recombinant Human Uteroglobin Fragment (residues 22-91) is a highly pure and stable protein designed for structural and functional studies. This 70-amino acid fragment retains key functional domains, including phospholipid-binding regions, making it an ideal tool for investigating anti-inflammatory mechanisms and ligand interactions in biochemical assays.
Uteroglobin, also known as Club cell phospholipid-binding protein (CCPBP) or Secretoglobin family 1A member 1 (SCGB1A1), is a secreted human protein that binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB), and weakly binds progesterone. It functions as a potent inhibitor of phospholipase A2, playing a critical role in modulating inflammatory responses through its phospholipid-binding capacity. As a secreted protein, it operates extracellularly, contributing to its significance in pulmonary biology and potential therapeutic applications.
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Protein name
Uteroglobin
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Uniprot ID
P11684
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Gene Name
SCGB1A1; CC10; CCSP; UGB
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 22-91 aa (P11684) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 9.57 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 10 kDa band.
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Purity
>87%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"