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Product Name
Recombinant UFSP1 protein (His tag)
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Description
Recombinant Human Ufm1-specific protease 1 (UfSP1) fragment (residues 1-218) is a high-purity protein designed for structural and biochemical studies. This fragment represents a stable, soluble unit of the enzyme, ideal for investigating its role in UFM1 precursor processing and deconjugation mechanisms.
Ufm1-specific protease 1 (UfSP1) is a thiol-dependent isopeptidase essential for the maturation of UFM1 precursors and the deconjugation of UFM1 from target proteins, a prerequisite for UFM1-mediated conjugation reactions. It primarily localizes to the cytoplasm and cytosol, where it regulates key cellular processes. The provided fragment (residues 1-218) encompasses the functional domain critical for its protease activity, enabling detailed analysis of its mechanism and interactions.
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Protein name
Ufm1-specific protease 1
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Uniprot ID
Q6NVU6
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Gene Name
UFSP1
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 1-218 aa (Q6NVU6) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 24.91 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 25 kDa band.
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Purity
>87%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"