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Recombinant UDB11 protein (His tag)

Recombinant UDB11 protein (His tag)

Cat.#: 549705

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Special Price 383.1 USD

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Product Information

  • Product Name
    Recombinant UDB11 protein (His tag)
  • Documents
  • Description

    Recombinant Human UDP-glucuronosyltransferase 2B11 (UDPGT 2B11) Fragment (residues 22-492) is a high-quality protein product designed for structural and biochemical studies. This 471-amino acid fragment represents a stable, soluble unit of the enzyme, optimized for research applications involving xenobiotic metabolism and detoxification pathways.

    UDP-glucuronosyltransferase 2B11 (EC 2.4.1.17) plays a critical role in phase II metabolism by catalyzing the conjugation of UDP-glucuronic acid to various endogenous compounds and xenobiotics, facilitating their elimination from the body. This enzyme is membrane-bound, localized primarily to the endoplasmic reticulum and microsomal membranes as a single-pass membrane protein. The full-length protein is of major importance in detoxification processes, making it a significant target for pharmacological and toxicological research.

  • Protein name
    UDP-glucuronosyltransferase 2B11
  • Uniprot ID
    O75310
  • Gene Name
    UGT2B11
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    DNA encoding 22-492 aa (O75310) were fused with 6His tag.
  • Sequence 
    22-492
  • Protein Species
    Human
  • Molecular weight
    Predictes a molecular mass of 56.06 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 56 kDa band.
  • Purity
    >87%, by SDS-PAGE with Coomassie Brilliant Blue staining.
  • Activity
    Not tested.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"