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  • TRH-Potentiating Peptide, Prepro TRH (160-169)

TRH-Potentiating Peptide, Prepro TRH (160-169)

Not For Human Use, Lab Use Only.

Cat.#: 315472

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* Buy 1 get 1 free (?) What is TFA?

Special Price 126.50 USD

Availability: 1-2 weeks
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Product Information

  • Product Name
    TRH-Potentiating Peptide, Prepro TRH (160-169)
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    SFPWMESDVT
  • Sequence
    H-Ser-Phe-Pro-Trp-Met-Glu-Ser-Asp-Val-Thr-OH
  • Length (aa)
    10
  • Peptide Purity (HPLC)
    96.1%
  • Molecular Formula
    C54H75N11O18S
  • Molecular Weight
    1198.32
  • CAS No.
    122018-91-1
  • Source
    Synthetic
  • Form
    Powder
  • Description
    This neuropeptide, originally isolated from bovine hypothalamus, corresponds to the deduced rat prepro TRH (160-169) sequence and gives the first direct chemical evidence for non-TRH peptides originating from the TRH precursor in vivo. The decapeptide potentiates the TRH-evoked thyrotropin secretion by the antehypophysis in vitro.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • M.Bulant et al., Proc. Natl. Acad. Sci. USA, 87, 4439 (1990)
    • J.-P.Roussel et al., Neuroendocrinology, 54, 559 (1991)
    • M.Bulant et al., Biochem. Biophys. Res. Commun., 189, 1110 (1992)
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight

Peptide Property

  • Analysed Sequence:H-SFPWMESDVT-OH
  • Chemical Formula:C54H75N11O18S
  • Sequence length:10
  • Extinction coefficient:5690 M-1cm-1
  • GRAVY:-0.29
  • Mw average:1198.29
  • Theoretical pI:3.01
  • Data Source:Peptide Property Calculator

GRAVY = grand average of hydropathy

X: Hydrophobic uncharged residues, like F I L M V W A and P

X: Basic residues, like R K H

X: Acidic residues, like D E

X: Polar uncharged residues, like G S T C N Q and Y

• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"