Cart 2
  • TuberoInfundibular peptide, TIP39

TuberoInfundibular peptide, TIP39

Not For Human Use, Lab Use Only.

Cat.#: 301919

Size:

* Buy 1 get 1 free (?) What is TFA?

Special Price 493.40 USD

Availability: 4 weeks
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    TuberoInfundibular peptide, TIP39
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    SLALADDAAFRERARLLAALERRHWLNSYMHKLLVLDAP
  • Sequence
    H-Ser-Leu-Ala-Leu-Ala-Asp-Asp-Ala-Ala-Phe-Arg-Glu-Arg-Ala-Arg-Leu-Leu-Ala-Ala-Leu-Glu-Arg-Arg-His-Trp-Leu-Asn-Ser-Tyr-Met-His-Lys-Leu-Leu-Val-Leu-Asp-Ala-Pro-OH
  • Length (aa)
    39
  • Peptide Purity (HPLC)
    97.2%
  • Molecular Formula
    C202H325N61O54S
  • Molecular Weight
    4504.25 net
  • CAS No.
    277302-47-3
  • Source
    Synthetic
  • Form
    Powder
  • Description
    This new polypeptide originally isolated from bovine hypothalamus was found to be a potent and selective agonist of the pTH2 receptor which regulates pituitary hormone secretion and spinal cord regions involved in pain perception. Synthetic TIP-39 activated the human and rat pTH2 receptors with EC50 of 0.5 ± 0.12 nM and 0.8 ± 0.3 nM, respectively. TIP-39 was much more potent than pTH (EC50 = 49 ± 23 nM) at the rat pTH2 receptor. The discovery of TIP-39
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • T.B.Usdin et al., Nat. Neurosci., 2, 941 (1999)
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight

Peptide Property

  • Analysed Sequence:H-SLALADDAAFRERARLLAALERRHWLNSYMHKLLVLDAP-OH
  • Chemical Formula:C202H325N61O54S
  • Sequence length:39
  • Extinction coefficient:6970 M-1cm-1
  • GRAVY:-0.04
  • Mw average:4504.16
  • Theoretical pI:9.71
  • Data Source:Peptide Property Calculator

GRAVY = grand average of hydropathy

X: Hydrophobic uncharged residues, like F I L M V W A and P

X: Basic residues, like R K H

X: Acidic residues, like D E

X: Polar uncharged residues, like G S T C N Q and Y

• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"