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Product Name
Recombinant THSD1 protein (His tag)
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Description
Recombinant Human THSD1 (Thrombospondin type-1 domain-containing protein 1) Fragment (aa 25-413): A high-purity protein fragment encompassing the critical TSP type-1 domain, engineered to support studies in endothelial cell adhesion and focal adhesion dynamics.
Thrombospondin type-1 domain-containing protein 1 (THSD1) is a transmembrane protein that functions as a positive regulator of nascent focal adhesion assembly and modulates endothelial cell attachment to the extracellular matrix. It localizes to endosome membranes, focal adhesions, and cell junctions, playing a key role in cellular adhesion processes. The provided fragment (aa 25-413) includes the functional TSP type-1 domain (aa 340-393), enabling targeted investigation of domain-specific mechanisms in adhesion biology.
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Protein name
Thrombospondin type-1 domain-containing protein 1
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Uniprot ID
Q9NS62
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Gene Name
THSD1; TMTSP
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 25-413 aa (Q9NS62) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 45.12 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 45 kDa band.
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Purity
>85%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"