Temporin B peptide

Temporin B peptide

• COA/MS/HPLC Report
• Handling and Storage of Synthetic Peptides
• Material Safety Data Sheets (MSDS)

Batch to batch variation of the purity

LLPIVGNLLKSLL-NH2

H-Leu-Leu-Pro-Ile-Val-Gly-Asn-Leu-Leu-Lys-Ser-Leu-Leu-NH2

13

99.25%

C₆₇H₁₂₁N₁₅O₁₆

1391.76

188713-70-4

Synthetic

Powder

C-terminal amidated. Active against B. megaterium Bm11, S. aureus Cowan1, Y. pseudotubercolosis, S. pyogenes beta hem. group A (MIC 2.8-7 uM), E. coli D21 (MIC 21 uM), and C. albicans (MIC 4 uM). Also E. coli (MIC 12.5-50 uM), S. aureus (12-48 uM), and A. baumannii (MIC (24 uM).The D-form was found to be more active and stable than the L-form (D>L; Herin OH et al 2000 Antimicrob Agents Chemother 44:68-72). Updated 2/23/2012 GW & BM; 3/2015 GW. Temporin B has Antibacterial, Antifungal activity. Temporin B was found in European common frog, Rana temporaria.

Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• Simmaco M, Mignogna G, Canofeni S, Miele R, Mangoni ML, Barra D. Temporins, antimicrobial peptides from the European red frog Rana temporaria. Eur J Biochem. 1996;242(3):788-92.

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.