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  • TAT peptide

TAT peptide

Not For Human Use, Lab Use Only.

Cat.#: 319506

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Special Price 122.30 USD

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Product Information

  • Product Name
    TAT peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    H-YGRKKRRQRRRC-OH
  • Sequence
    H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Cys-OH
  • Length (aa)
    12
  • Peptide Purity (HPLC)
    95.1%
  • Molecular Formula
    C67H123N33O15S
  • Molecular Weight
    1662.97
  • Source
    Synthetic
  • Form
    Powder
  • Description
    The transactivating transcriptional activator (TAT) peptide, a cell-penetrating peptide with a specific amino acid sequence (YGRKKRRQRRRC), which has the special ability to aid translocation across the plasma membrane, is widely used to modify the anticancer drug carriers, and indeed improve the drug accumulation deep in tumor tissues.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Shuai Q, Cai Y, Zhao G, Sun X. Cell-Penetrating Peptide Modified PEG-PLA Micelles for Efficient PTX Delivery. Int J Mol Sci. 2020 Mar 9;21(5):1856. doi: 10.3390/ijms21051856. PMID: 32182734; PMCID: PMC7084196.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"