Tachykinin-related peptide, TRP2

Tachykinin-related peptide, TRP2

• Handling and Storage of Synthetic Peptides
• Material Safety Data Sheets (MSDS)

Batch to batch variation of the purity

ALMGFQGVR-amide

H-Ala-Leu-Met-Gly-Phe-Gln-Gly-Val-Arg-NH2

9

95.8%

C₄₃H₇₁N₁₃O₁₁S

977.18

Synthetic

Powder

The source of Tachykinin-related peptide, TRP2 is honeybee (Apis mellifera). Tachykinins (TKs) form a family of neuropeptides in vertebrates with a consensus C-terminal region (F-X-G-Y-R-NH2). Found in invertebrates, TK-related peptides (TKRPs) constitute subfamilies sharing significant sequence homology with vertebrate TKs and displaying similar biological activities, including both neuropeptide and antimicrobial functions.

Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• Takeuchi H, Yasuda A, Yasuda-kamatani Y, Kubo T, Nakajima T. Identification of a tachykinin-related neuropeptide from the honeybee brain using direct MALDI-TOF MS and its gene expression in worker, queen and drone heads. Insect Mol Biol. 2003;12(3):291-8.
• Han B, Wei Q, Wu F, Hu H, Ma C, Meng L, Zhang X, Feng M, Fang Y, Rueppell O, Li J. Tachykinin signaling inhibits task-specific behavioral responsiveness in honeybee workers. Elife. 2021 Mar 24;10:e64830. doi: 10.7554/eLife.64830. PMID: 33760729; PMCID: PMC8016481.

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.