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Product Name
Recombinant SURF1 protein (His tag)
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Description
Recombinant Surfeit locus protein 1 (SURF1) fragment (amino acids 80-273) is a high-purity, stable protein designed for structural and biochemical studies. This 194-amino acid fragment, derived from human SURF1, represents a soluble and functionally relevant unit ideal for investigating mitochondrial cytochrome c oxidase assembly mechanisms.
Surfeit locus protein 1 (SURF1) is a multi-pass membrane protein localized to the mitochondrial inner membrane. It functions as a component of the MITRAC complex, which plays a critical role in regulating the assembly of cytochrome c oxidase—an essential enzyme in the mitochondrial respiratory chain. The full-length protein's involvement in maintaining oxidative phosphorylation underscores its significance in cellular energy production and mitochondrial health.
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Protein name
Surfeit locus protein 1
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Uniprot ID
Q15526
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Gene Name
SURF1; SURF-1
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 80-273 aa (Q15526) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 23.71 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 24 kDa band.
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Purity
>88%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"