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  • Suc-Leu-Leu-Val-Tyr-AMC peptide

Suc-Leu-Leu-Val-Tyr-AMC peptide

Not For Human Use, Lab Use Only.

Cat.#: 319625

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* Buy 1 get 1 free (?) What is TFA?

Special Price 279.00 USD

Availability: 1-2 weeks
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Product Information

  • Product Name
    Suc-Leu-Leu-Val-Tyr-AMC peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    Suc-LLVY-AMC
  • Sequence
    Suc-Leu-Leu-Val-Tyr-AMC
  • Length (aa)
    4
  • Peptide Purity (HPLC)
    95.49%
  • Molecular Formula
    C40H53N5O10
  • Molecular Weight
    763.87
  • CAS No.
    94367-21-2
  • PubChem CID
    10234210
  • Source
    Synthetic
  • Form
    Powder
  • Description
    The peptide Suc-Leu-Leu-Val-Tyr-AMC (succinyl-Leu-Leu-Val-Tyr-amidomethylcoumarin) is a fluorogenic peptide substrate to assay the chymotrypsin-like activity of mammalian 20S and 26S proteasomes.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Debiasi RL, Squier MK, Pike B, Wynes M, Dermody TS, Cohen JJ, Tyler KL. Reovirus-induced apoptosis is preceded by increased cellular calpain activity and is blocked by calpain inhibitors. J Virol. 1999 Jan;73(1):695-701. doi: 10.1128/JVI.73.1.695-701.1999. PMID: 9847375; PMCID: PMC103876.
    • Gardner RC, Assinder SJ, Christie G, Mason GG, Markwell R, Wadsworth H, McLaughlin M, King R, Chabot-Fletcher MC, Breton JJ, Allsop D, Rivett AJ. Characterization of peptidyl boronic acid inhibitors of mammalian 20 S and 26 S proteasomes and their inhibition of proteasomes in cultured cells. Biochem J. 2000 Mar 1;346 Pt 2(Pt 2):447-54. PMID: 10677365; PMCID: PMC1220872.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"