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Product Name
Recombinant STK31 protein (His tag)
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Description
Recombinant Human Serine/threonine-protein kinase 31 (STK31) Fragment (aa 32-212) is a high-purity protein preparation containing the complete Tudor domain (aa 78-137). This domain-specific fragment serves as an essential research tool for investigating Tudor domain-mediated functions, including potential roles in epigenetic regulation and protein-protein interactions.
Serine/threonine-protein kinase 31 (STK31), also known as Sugen kinase 396, is a human protein kinase belonging to the EC 2.7.11.1 enzyme classification. While specific functional details and subcellular localization information are not fully characterized in the provided data, the presence of the Tudor domain within this fragment suggests potential involvement in recognizing methylated histone marks and mediating chromatin-related processes. The Tudor domain is known to function as an epigenetic reader domain that specifically binds methylated lysine and arginine residues on histone tails, positioning STK31 as a potential regulator of chromatin structure and gene expression.
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Protein name
Serine/threonine-protein kinase 31
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Uniprot ID
Q9BXU1
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Gene Name
STK31; SGK396
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 32-212 aa (Q9BXU1) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 21.98 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 23 kDa band.
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Purity
>85%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"