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Recombinant STK10 protein (His tag)

Cat.#: 539593

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Product Information

  • Product Name
    Recombinant STK10 protein (His tag)
  • Documents
  • Description

    Recombinant Human Serine/threonine-protein kinase 10 (STK10) fragment (amino acids 1-317) is a high-purity protein encompassing the full protein kinase domain. This product serves as an essential tool for investigating kinase activity, lymphocyte migration regulation, and cell cycle control mechanisms in biochemical and cellular assays.

    Serine/threonine-protein kinase 10 (STK10), also known as Lymphocyte-oriented kinase, is a human enzyme (EC 2.7.11.1) that plays a critical role in regulating lymphocyte migration through phosphorylation of ERM proteins such as moesin (MSN). It functions as a negative regulator of MAP3K1/MEKK1 and may act as a cell cycle regulator through potential phosphorylation of PLK1, though in vivo evidence is still required. The protein localizes to the cell membrane as a peripheral membrane protein, positioning it strategically for signal transduction and cellular regulation processes.

  • Protein name
    Serine/threonine-protein kinase 10
  • Uniprot ID
    O94804
  • Gene Name
    STK10; LOK
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    DNA encoding 1-317 aa (O94804) were fused with C-terminal 6His tag.
  • Sequence 
    MAFANFRRIL RLSTFEKRKS REYEHVRRDL DPNEVWEIVG ELGDGAFGKV YKAKNKETGA LAAAKVIETK SEEELEDYIV
EIEILATCDH PYIVKLLGAY YHDGKLWIMI EFCPGGAVDA IMLELDRGLT EPQIQVVCRQ MLEALNFLHS KRIIHRDLKA
GNVLMTLEGD IRLADFGVSA KNLKTLQKRD SFIGTPYWMA PEVVMCETMK DTPYDYKADI WSLGITLIEM AQIEPPHHEL
NPMRVLLKIA KSDPPTLLTP SKWSVEFRDF LKIALDKNPE TRPSAAQLLE HPFVSSITSN KALRELVAEA KAEVMEELEH
HHHHH
  • Protein Species
    Human
  • Molecular weight
    Predictes a molecular mass of 37.17 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 41 kDa band.
  • Purity
    >85%, by SDS-PAGE with Coomassie Brilliant Blue staining.
  • Activity
    Not tested.
  • Validations

    Recombinant STK10 protein (His tag) SDS-PAGE

    Recombinant STK10 protein (His tag) SDS-PAGE

    Lane 1: STK10;Lane 2: BSA

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"