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  • SSX2 41-49 peptide

SSX2 41-49 peptide

Not For Human Use, Lab Use Only.

Cat.#: 319185

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Product Information

  • Product Name
    SSX2 41-49 peptide
  • Documents
  • Sequence Shortening
    H-KASEKIFYV-OH
  • Sequence
    H-Lys-Ala-Ser-Glu-Lys-Ile-Phe-Tyr-Val-OH
  • Length (aa)
    9
  • Peptide Purity (HPLC)
    95.92%
  • Molecular Formula
    C52H81N11O14
  • Molecular Weight
    1084.26
  • Source
    Synthetic
  • Form
    Powder
  • Description
    The SSX2 41-49 peptide (KASEKIFYV) corresponding to amino acids 41 to 49 of SSX2. SSX2 41-49 (KASEKIFYV) peptide showed specific reactivity, tumor cell recognition and tetramer binding. IFNg release induced by SSX2 41-49 peptide was two to four orders of magnitude superior to that induced by the homologous peptides, confirming the specificity of TCR-5.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual:Handling and Storage of Synthetic Peptides
  • References
    • Abate-Daga D, Speiser DE, Chinnasamy N, Zheng Z, Xu H, Feldman SA, Rosenberg SA, Morgan RA. Development of a T cell receptor targeting an HLA-A*0201 restricted epitope from the cancer-testis antigen SSX2 for adoptive immunotherapy of cancer. PLoS One. 2014 Mar 28;9(3):e93321.
  • About TFA salt

    Trifluoroacetic acid (TFA) has a significant impact on peptides due to its role in the peptide synthesis process.

    TFA is essential for the protonation of peptides that lack basic amino acids such as Arginine (Arg), Histidine (His), and Lysine (Lys), or ones that have blocked N-termini. As a result, peptides often contain TFA salts in the final product.

    TFA residues, when present in custom peptides, can cause unpredictable fluctuations in experimental data. At a nanomolar (nM) level, TFA can influence cell experiments, hindering cell growth at low concentrations (as low as 10 nM) and promoting it at higher doses (0.5–7.0 mM). It can also serve as an allosteric regulator on the GlyR of glycine receptors, thereby increasing receptor activity at lower glycine concentrations.

    In an in vivo setting, TFA can trifluoroacetylate amino groups in proteins and phospholipids, inducing potentially unwanted antibody responses. Moreover, TFA can impact structure studies as it affects spectrum absorption.

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"