Recombinant SRF protein (His tag)

Recombinant SRF protein (His tag)

Cat.#: 542113

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Product Information

  • Product Name
    Recombinant SRF protein (His tag)
  • Documents
  • Description

    Recombinant Human Serum Response Factor (SRF) Fragment (aa 137-226) – a high-purity protein fragment encompassing the essential MADS-box domain, designed for targeted studies of SRF's transcriptional regulation and cytoskeletal gene expression mechanisms.

    Serum Response Factor (SRF) is a key transcription factor in humans that binds to the serum response element (SRE) to regulate genes such as FOS. It partners with the MRTFA coactivator to control cytoskeletal gene expression in response to Rho GTPase signaling and actin dynamics, playing critical roles in development, morphogenesis, cell migration, and cardiac differentiation. SRF is localized to the nucleus, where it orchestrates gene expression programs essential for cellular structure and function.

  • Protein name
    Serum response factor
  • Uniprot ID
    P11831
  • Gene Name
    SRF
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    DNA encoding 137-226 aa (P11831) were fused with 6His tag.
  • Protein Species
    Human
  • Molecular weight
    Predictes a molecular mass of 11.77 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 12 kDa band.
  • Purity
    >90%, by SDS-PAGE with Coomassie Brilliant Blue staining.
  • Activity
    Not tested.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"