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Product Name
Recombinant SNR25 protein (His tag)
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Description
Recombinant Human U11/U12 snRNP 25 kDa Protein Fragment (SNRNP25, residues 1-132) is a high-purity, biologically active protein designed for studying the specific functions of its ubiquitin-like domains. This fragment serves as an essential tool for researchers investigating RNA splicing mechanisms and nuclear processes.
The full-length U11/U12 small nuclear ribonucleoprotein 25 kDa protein, encoded by the SNRNP25 gene, is a nuclear-localized protein (as indicated by its subcellular location: Nucleus {ECO:0000269|PubMed:15146077}). It is a component of the U11/U12 snRNP complex, which plays a critical role in minor spliceosome assembly and the splicing of U12-type introns, contributing to mRNA processing and gene expression regulation in humans.
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Protein name
U11/U12 small nuclear ribonucleoprotein 25 kDa protein
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Uniprot ID
Q9BV90
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Gene Name
SNRNP25; C16orf33
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 1-132 aa (Q9BV90) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 16.92 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 17 kDa band.
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Purity
>86%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"