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Recombinant SIG16 protein (His tag)

Cat.#: 548885

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Product Information

  • Product Name
    Recombinant SIG16 protein (His tag)
  • Documents
  • Description

    Recombinant Human Sialic acid-binding Ig-like lectin 16 (Siglec-16) Fragment (aa 17-434) is a high-purity protein designed to encompass the complete Ig-like V-type and C2-type domains, enabling focused investigation into sialic-acid dependent binding and cellular adhesion mechanisms.

    Sialic acid-binding Ig-like lectin 16 (Siglec-16) is a putative adhesion molecule in humans that facilitates sialic-acid dependent binding to cells, suggesting roles in intercellular recognition and immune modulation. As a single-pass type I membrane protein localized to the cell membrane, it functions at the cell surface to mediate specific molecular interactions critical for cellular communication. This recombinant fragment allows targeted study of its functional domains without membrane-associated complexities.

  • Protein name
    Sialic acid-binding Ig-like lectin 16
  • Uniprot ID
    A6NMB1
  • Gene Name
    SIGLEC16; SIGLECP16
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    DNA encoding 17-434 aa (A6NMB1) were fused with C-terminal 6His tag.
  • Sequence 
    MSKIKNKDPS YSLQVQRQVP VPEGLCVIVS CNLSYPRDGW DESTAAYGYW FKGRTSPKTG APVATNNQSR EVAMSTRDRF
QLTGDPGKGS CSLVIRDAQR EDEAWYFFRV ERGSRVRHSF LSNAFFLKVT ALTQKPDVYI PETLEPGQPV TVICVFNWAF
KKCPAPSFSW TGAALSPRRT RPSTSHFSVL SFTPSPQDHD TDLTCHVDFS RKGVSAQRTV RLRVASLELQ GNVIYLEVQK
GQFLRLLCAA DSQPPATLSW VLQDRVLSSS HPWGPRTLGL ELPGVKAGDS GRYTCRAENR LGSQQRALDL SVQYPPENLR
VMVSQANRTV LENLRNGTSL RVLEGQSLRL VCVTHSSPPA RLSWTWGEQT VGPSQPSDPG VLQLPRVQME HEGEFTCHAR
HPLGSQRVSL SFSVHCKSGP MTGLEHHHHH H
  • Protein Species
    Human
  • Molecular weight
    Predictes a molecular mass of 48.06 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 48 kDa band.
  • Purity
    >85%, by SDS-PAGE with Coomassie Brilliant Blue staining.
  • Activity
    Not tested.
  • Validations

    Recombinant SIG16 protein (His tag) SDS-PAGE

    Recombinant SIG16 protein (His tag) SDS-PAGE

    M: Marker; Lane 1: SIG16; Lane 2: BSA

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"