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  • Secretogranin-2 precursor [184-216] peptide

Secretogranin-2 precursor [184-216] peptide

Not For Human Use, Lab Use Only.

Cat.#: 315206

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Product Information

  • Product Name
    Secretogranin-2 precursor [184-216] peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    TNEIVEEQYTPQSLATLESVFQELGKLTGPSNQ
  • Sequence
    Thr-Asn-Glu-Ile-Val-Glu-Glu-Gln-Tyr-Thr-Pro-Gln-Ser-Leu-Ala-Thr-Leu-Glu-Ser-Val-Phe-Gln-Glu-Leu-Gly-Lys-Leu-Thr-Gly-Pro-Ser-Asn-Gln
  • Length (aa)
    33
  • Peptide Purity (HPLC)
    95.3%
  • Molecular Formula
    C159H252N40O58
  • Molecular Weight
    3651.98
  • CAS No.
    149146-12-3
  • Source
    Synthetic
  • Form
    Powder
  • Description
    Secretogranin II (154-186) (Secretoneurin) is a neuropeptide generated in brain, adrenal medulla and other endocrine tissues by proteolytic processing of secretogranin II (chromogranin C). It enhances dopamine release in a concentration-dependent manner. A role in neuro-immunological processes has been proposed due to its capability to act as chemoattractant for eosinophils and monocytes. Significant changes of secretoneurin-like immunoreactivity occur in Alzheimer's disease, reflecting synaptic loss.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Boonen K, Baggerman G, D'hertog W, et al. Neuropeptides of the islets of Langerhans: a peptidomics study. Gen Comp Endocrinol. 2007;152(2-3):231-41.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight

Peptide Property

  • Analysed Sequence:H-TNEIVEEQYTPQSLATLESVFQELGKLTGPSNQ-OH
  • Chemical Formula:C159H252N40O58
  • Sequence length:33
  • Extinction coefficient:1280 M-1cm-1
  • GRAVY:-0.61
  • Mw average:3651.91
  • Theoretical pI:3.67
  • Data Source:Peptide Property Calculator

GRAVY = grand average of hydropathy

X: Hydrophobic uncharged residues, like F I L M V W A and P

X: Basic residues, like R K H

X: Acidic residues, like D E

X: Polar uncharged residues, like G S T C N Q and Y

• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"