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  • Saralasin peptide

Saralasin peptide

Not For Human Use, Lab Use Only.

Cat.#: 319044

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* Buy 1 get 1 free (?) What is TFA?

Special Price 178.60 USD

Availability: 1-2 weeks
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Product Information

  • Product Name
    Saralasin peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    XRVYVHPA, X = Sarcosine
  • Sequence
    Sar-Arg-Val-Tyr-Val-His-Pro-Ala-OH
  • Length (aa)
    7
  • Peptide Purity (HPLC)
    95.62%
  • Molecular Formula
    C42H65N13O10
  • Molecular Weight
    912.0
  • Source
    Synthetic
  • Form
    Powder
  • Description
    Saralasin, also known as [Sar1,Val5, Ala8] angiotensin II is an angiotensin II analog with substitutions to the angiotensin II sequence of sarcosine at position 1, valine at position 5,and alanine at position 8. Saralasin is a partial agonist of the angiotensin II receptor, and is used to treat hypertension.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Steinhausen et al (1986) Angiotensin II control of the renal microcirculation: effect of blockade by saralasin. Kidney Int. 30 56 PMID: 3747343
    • Thomas et al (1995) Saralasin suppresses arrhythmias in an isolated guinea-pig ventricular free wall model of simulated ischemia and reperfusion. J.Pharmacol.Exp.Ther. 274 1379 PMID: 7562511
    • Guimond et al (2014) Saralasin and Sarile Are AT2 Receptor Agonists. ACS Med. Chem. Lett. 5(10) 1129 PMID: 25313325
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"