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  • Rp-1 peptide

Rp-1 peptide

Not For Human Use, Lab Use Only.

Cat.#: 300765

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* Buy 1 get 1 free (?) What is TFA?

Special Price 227.70 USD

Availability: 1-2 weeks
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Product Information

  • Product Name
    Rp-1 peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    H-ALYKKFKKKLLKSLKRLG-OH
  • Sequence
    H-Ala-Leu-Tyr-Lys-Lys-Phe-Lys-Lys-Lys-Leu-Leu-Lys-Ser-Leu-Lys-Arg-Leu-Gly-OH
  • Length (aa)
    18
  • Peptide Purity (HPLC)
    96.6%
  • Molecular Formula
    C104H184N28O21
  • Molecular Weight
    2162.74
  • Source
    Synthetic
  • Form
    Powder
  • Description
    RP-1 is an 18-amino-acid peptide modeled in part upon α-helical C-terminal microbicidal domains of mammalian CXCL4 kinocidins. RP-1 has some structural similarities with the antimicrobial peptide C18G. RP-1 is an antimicrobial peptide, and is active against S. aureus, S. typhimurium, E. coli, and C. albicans.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Erfe MC, David CV, Huang C, Lu V, Maretti-Mira AC, Haskell J, Bruhn KW, Yeaman MR, Craft N. Efficacy of synthetic peptides RP-1 and AA-RP-1 against Leishmania species in vitro and in vivo. Antimicrob Agents Chemother. 2012 Feb;56(2):658-65. doi: 10.1128/AAC.05349-11. Epub 2011 Nov 28. PMID: 22123683; PMCID: PMC3264259.
    • Yeaman MR, Gank KD, Bayer AS, Brass EP. Synthetic peptides that exert antimicrobial activities in whole blood and blood-derived matrices. Antimicrob Agents Chemother. 2002 Dec;46(12):3883-91. doi: 10.1128/AAC.46.12.3883-3891.2002. PMID: 12435692; PMCID: PMC132762.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"