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Product Name
Recombinant RET4 protein (His tag)
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Description
Recombinant Human Retinol-binding protein 4 (RBP4) fragment (amino acids 19-201) is a high-quality protein product designed for research applications. This 183-amino acid fragment represents a stable and soluble unit of plasma retinol-binding protein, ideal for structural studies, biochemical assays, and functional investigations of retinol transport mechanisms.
Retinol-binding protein 4 (RBP4) is a plasma protein that mediates retinol transport in blood circulation. It functions to deliver retinol from hepatic stores to peripheral tissues, playing a crucial role in vitamin A distribution throughout the body. The protein facilitates the transfer of bound all-trans retinol to STRA6 receptors, enabling cellular uptake of retinol across membranes. As a secreted protein, RBP4 circulates in blood plasma where it maintains retinol solubility and targeted delivery to tissues requiring vitamin A for various physiological processes including vision, immune function, and cellular differentiation.
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Protein name
Retinol-binding protein 4
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Uniprot ID
P02753
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Gene Name
RBP4
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 19-201 aa (P02753) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 22.73 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 24 kDa band.
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Purity
>87%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"