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Product Name
Recombinant RABEK protein (His tag)
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Description
Recombinant Human Rab9 effector protein with kelch motifs (p40) fragment (residues 1-306) is a high-quality, stable protein designed for structural and biochemical studies. This 306-amino acid fragment represents a soluble and functional unit of the full-length protein, ideal for investigating its role in endosome-to-TGN transport and Rab9-mediated cellular processes.
The full-length Rab9 effector protein with kelch motifs (p40), encoded by the RABEPK gene, functions as a Rab9 effector essential for endosome-to-trans-Golgi network (TGN) transport. It localizes to the cytoplasm and endosome membrane, where interaction with PIKFYVE and subsequent phosphorylation recruits it to endosomal membranes, facilitating intracellular trafficking pathways critical for cellular organization and protein sorting.
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Protein name
Rab9 effector protein with kelch motifs
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Uniprot ID
Q7Z6M1
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Gene Name
RABEPK; RAB9P40
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 1-306 aa (Q7Z6M1) were fused with 6His tag.
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Sequence
1-306
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 35.10 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 35 kDa band.
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Purity
>87%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"